Timothy Dwyer: Fine School of the Sciences Faculty
Timothy Dwyer , Ph.D.
- Ph.D. Biochemistry, Dartmouth Medical School 1995
- B.S. Chemistry, Regis College 1988
- B.S. Biology, Regis College 1988
Professor of Chemistry
Associate Professor of Chemistry
Assistant Professor of Chemistry
UNIVERSITY OF COLORADO HEALTH SCIENCES
1999 Summer Instructor
UNIVERSITY OF DENVER
1999 Spring Adjunct Faculty
Cancer has affected just about everyone in some way. Research in my lab focuses on lessening the adverse effects of two commonly used chemotherapeutic agents, docetaxel and doxorubicin, and improving treatment and quality of life for cancer patients. Students working in the lab will work with a specific enzyme, Malate Dehydrogenase, and discover how inhibition of this enzyme can help the cancer patients.
- “Combining Inquiry-Based and Team-Teaching Models to Design a Research-Driven, Cross-Disciplinary Laboratory Course” Burkett, Jeremy R., Dwyer, Timothy M. Journal of Chemical Education. 2019, 96, 660-667.
- Timothy M. Dwyer, Rivka L. Glaser, and Tracey M. Mason. Inheritance Patterns in Human Phenotypes and Types of Genetic Disorders. Lashley’s Essentials of Clinical Genetics in Nursing Practice 2nd Edition. 2016 Springer Publishing Company, Christine E. Kasper, Tonya A. Schneidereith, and Felissa Lashley, editors.
- Katherine J. Denniston, Joseph J. Topping and Timothy M. Dwyer. Student Study Guide/Solutions Manual to Accompany Foundations of General, Organic, and Biochemistry. 2008, McGraw Hill, 568 pages.
- Katherine J. Denniston, Joseph J. Topping and Timothy M. Dwyer. Instructors Manual to Accompany Foundations of General, Organic, and Biochemistry. 2008, McGraw Hill, 217 pages.
- Albro, M., Rao, K. S., Dwyer, T. M., and Frerman, F. E. “Kinetic Mechanism of Human Glutaryl-CoA Dehydrogenase.” Biochemistry 2006, 46(51):15853-61
- Katherine J. Denniston, Joseph J. Topping and Timothy M. Dwyer. Student Study Guide/Solutions Manual to Accompany General, Organic, and Biochemistry; Fifth Edition. 2005, McGraw Hill, 569 pages.
- Katherine J. Denniston, Joseph J. Topping and Timothy M. Dwyer. Instructors Manual to Accompany General, Organic, and Biochemistry; Fifth Edition. 2005, McGraw Hill, 95 pages.
- Frank R. Milio, Liina Ladon, Tim M. Dwyer, and Mark S. Profili. (2004) -Taking the Initiative In Forensic Chemistry Education at Towson University. Forensic Magazine. 1 (Fall), 18-21.
- Rao, K. S., Vander Velde, D., Dwyer T. M., Goodman, S. I. and Frerman F. E. (2002) Alternate substrate of Human Glutaryl-CoA Dehydrogenase:structure and reactivity of the substrates and the Identification of a novel 2-enoyl-CoA product. Biochemistry, 41 (4), 1274-1284.
- Dwyer, T. M., Rao, K. S, Westover, J. B., Kim. J.-J., P. and Frerman, F. E. (2001) The function of Arg94 in the oxidation and decarboxylation of glutaryl-CoA by human glutaryl-CoA dehydrogenase . J. Biol. Chem., 276, 133-138.
- Dwyer, T. M., Rao, K. S., Goodman, S. I. and Frerman, F. E. (2000) Proton abstraction, steady state kinetics and oxidation-reduction potentials of human glutaryl-CoA dehydrogenase – Biochemistry, 39, 11488-11499.
- Dwyer, T. M., Mortle, S., Kemter, K., Bacher, A., Fauq, A. and Frerman, F. E. (1999) The intraflavin hydrogen bond in human electron transfer flavoprotein modulates redox potentials and may participate in electron transfer. Biochemistry, 38 (30), 9735-9745.
- Dwyer, T. M., Zhang, L., Muller, M. L., Marrugo, F., and Frerman, F. E. (1999) The functions of the flavin contact residues, aR249 and bY16, in human electron transfer flavoprotein. Biochim. Biophys. Acta, 1433, 139-152.
- Dwyer, T. M., Griffin, K. J. and Frerman, F. E. (1997) Investigation of the T244M mutation in the alpha subunit of Paracoccus denitrificans electron transfer flavoprotein, Flavin and Flavoproteins 1996 , (Stevenson, K. J., Massey, V. and Williams, C. H., Jr., Eds.) 519-522.
- Griffin, K. J., Dwyer, T. M., Manning, M. C., Meyer, J. D., Carpenter, J. F. and Frerman, F. E. (1996) aT244M mutation affects the redox, kinetic, and in vitro folding properties of Paracoccus denitrificans Electron Transfer Flavoprotein, Biochemistry. 36 (14), 4194-4202.
- Dwyer, T. M. and Froehner, S. C. (1995). Direct binding of Torpedo syntrophin to dystrophin and the 87kDa dystrophin homologue, FEBS Letters, 375, 91-94.
- Adams, M. E., Dwyer, T. M., Dowler, L. L., White, R. A. and Froehner, S. C. (1995). Mouse a1- and b2-syntrophin gene structure, chromosome localization, and homology with a discs large domain, J. Biol. Chem. 270 (43), 25859-25865.
- Adams, M. E., Butler, M. H., Dwyer T. M., Peters, M. F., Murnane, A. A. and Froehner, S. C. (1993). Two forms of mouse syntrophin, a 58kD dystrophin-associated protein, differ in primary structure and tissue distribution, Neuron, 11, 531-540.
BIOCH 327 - Biochemistry
BIOCH 345L - Integrative Laboratory 1
BIOCH 427 - Advanced Biochemistry
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